Wisehubby and I had been TTC for a while and, on a hunch, discovered his severe male factor infertility--basically, he has an army of mutant sperm. I'm also mutant; I have a clotting disorder: Factor V. We were on the IVF with ICSI track, and I gave birth to a beautiful boy after IVF #2. We've tried varicocele repair, too--ugh. Our frozen embyro transfer ended in miscarriage at 9 weeks 1 day. We don't know where the quest will take us from here.

Friday, December 21, 2012

Sick and tired

It's official: I am sick and tired. Not of being pregnant, although that is certainly contributing to the tired aspect. I'm actually sick, like porcupines have danced in my throat and the mucus is trying to drown me slowly sick. It came on fast, but I chose wisely to go see my doctor and get a note off from work for today--Merry Christmas!

Anyway, in all of this complaining about my upper respiratory infection, I actually do have some updates on the pregnancy front. We went to our first regular obstetric appointment on Wednesday, at exactly 9 weeks pregnant. Since we had an ultrasound at week 7 and everything looked great, this was just a vaginal exam and culture and a chance to talk with Dr. B about what to expect over the next seven months. Yes, we're only seven months away from the arrival of Wisebaby! Eek!

I was hoping that she would say that I could stop Crinone, but, to no avail, I have ten more days of the nasty stuff. I was also hoping that she would agree with the OBs of my fellow heterozygous Factor V'ers (Wisesister and my bestie from HS) and take me off of Lovenox. That was also to no avail. I appreciate the caution, as I don't want to lose Wisebaby or end up with some sort of life-endangering clot myself. I don't appreciate the fact that I will have been on Lovenox for almost a calendar year when this is all said and done. It's expensive; it's painful; it makes me want to cry a little.

On the Factor V front, the other thing that Dr. B wants to do is schedule an inducement for week 38-39 so that she can switch me to Heparin, which is a twice a day blood thinner, a few weeks before my delivery, and then off of it, timed perfectly, for delivery. As she said, she'd rather control the situation to preserve my cardio-pulmonary system and protect Wisebaby. Again, I appreciate that, but it will definitely be a different experience than the one that I had in my head. Of course, I don't know why I should have expected anything different since nothing about our Quest for Wisebaby has played out the way it should have.

So, Wisebaby is due on July 24, so his/her arrival should be scheduled sometime between July 10-17, just in time for my niece's third birthday. Until then, I'm going to hope to continue to be tired for then next few weeks, but praying that I won't get any more sick.

Wednesday, December 5, 2012

An Ace in the Hole

We've been calling our Wisembies Ace and Base over the last few weeks, and today we got to see for sure if one or both of them stuck.

Our sonographer was running behind, so it was maybe more hurried than we had anticipated because I needed to get back to my school by 1:05 for my sixth period class. She did give me a big hug and a congratulations, which felt so real and genuine  Wisehubby and I both agree that she is by far the best part of our fertility clinic.

Anyway, the big news is that we have an Ace in the hole! One of our Wisembies implanted and flourished. We were exactly 7 weeks today, but little Ace is measuring 7 weeks 1 day, and his heart rate (131.58) is very strong. We could see his heart beating with no problem, and it was crazy that we could see the yolk sack and umbilical cord distinct from Ace's little blobby body. He measured 10.81 millimeters long!

We feel like we've been playing the long game and have finally scored; it is amazing to see that something you have chased after for so long is truly coming to fruition. We know that the weeks and months ahead of us are long, and uncertain, but we're excited for this next phase in our quest for Wisebaby!


Friday, November 23, 2012

Thanksgiving

After ninety-three shots, I am starting to believe that this pregnancy thing might just stick. This cycle went so much more smoothly than the last one; not just because it actually worked, but for several other reasons. I am so thankful for the following changes in circumstances:

  1. We didn't have any major home repairs crop up during this IVF cycle.
  2. I wasn't taking graduate classes.
  3. My new boss is very easy going, so taking personal days and getting a substitute didn't stress me out.
  4. Someone--or many someones--in every aspect of my life (work, church, family, friends) knew about our cycle. Having people asking after you makes dealing with an exciting and stressful situation more pleasant. 
  5. As much as I bitched about Lovenox, it is relieving to know that the male Dr. B crossed every t and dotted every i in order to make this cycle perfect. Factor V probably didn't cause my early miscarriage or failed IVF cycle, but it definitely won't be the complication in this pregnancy.
  6. Wisehubby bravely put his balls on the line in order to get an improvement in his sperm quality that is barely quantifiable. There is no way of knowing how important this factor was, but we got much better quality embryos this cycle.
  7. Dr. B reduced my stimulation drugs down. I felt much less uncomfortable throughout the process, and we got fewer and healthier eggs.
  8. Wisehubby was even sweeter this time than last, which I didn't think was possible.
  9. Dr. B helped us with the costs of the lab, which is especially good considering the cost of the Crinone and Lovenox prescriptions is outrageous! Crinone costs $263 and Lovenox costs $200. The pharmacist at Walmart keeps asking if I really want my prescriptions. Uh, yeah!
  10. We got a frostie! Having a frozen blastocyst takes a lot of pressure off of the transferred ones. We probably couldn't afford another fresh cycle for a few years, so it is great to know we've got a back up hanging out in a lab down the road.
  11. So many of my infertile friendships are also in a good place right now. IWF, Dear Friend, and MyLazyOvaries (Twitter friend) all have had BFPs, and that is such a wonderful thing. 

Friday, November 16, 2012

Relaxing a touch

I'm relaxing a touch now that we've gotten through both blood tests, and my HCG levels are rising appropriately. I cannot wait to see the Wisebaby(ies) via ultrasound on December 5, but I guess I will have to.

Thursday, November 15, 2012

BFP! BFP! BFP! BFP! BFP!


So, I swore to Wisesister when she went with me to CVS to buy pregnancy tests that I wouldn't be that crazy lady who tortured herself by taking a million pregnancy tests. It turns out that I lied.

Sunday was six days past transfer, and by 5 PM I couldn't stop myself from peeing on a stick. Luckily, I was rewarded with a nice pink line. It's faint in the picture, but I swear it is there. It is about half as dark as the control line. I repeated my tests in the afternoon on Monday, Tuesday, and Wednesday. The only day that was really crazy to do was Wednesday, since I had already gotten the call from my RE that we were BFP according to the blood test. My HCG was 112, so that's good according to the nurse--I have zero frame of reference on this one.

Tuesday did freak me out because the line faded visibly from Monday, but I'm ninety percent sure it was because I chugged some water in order to try to pee again in a short period of time. I was done in by my over-hydration.

Since the only experiences that I've ever had with conceiving have ended with a BFN or a chemical pregnancy, I'm feeling decidedly anxious. However, always a believer in positive thinking, I am just chanting to myself BFP! BFP! BFP! all day long as I anxiously await the results from my beta HCG tomorrow to see if things are indeed rising the way they should.

Join me now: BFP! BFP! BFP! BFP! BFP!

Tuesday, November 6, 2012

Days Past Transfer


5-Day Transfer

Days Past
Transfer (DPT)
Embryo Development
OneThe blastocyst begins to hatch out of its shell
TwoThe blastocyst continues to hatch out of its shell and begins to attach itself to the uterus
ThreeThe blastocyst attaches deeper into the uterine lining, beginning implantation
FourImplantation continues
FiveImplantation is complete, cells that will eventually become the placenta and fetus have begun to develop
SixHuman chorionic gonadotropin (hCG) starts to enter the blood stream
SevenFetal development continues and hCG continues to be secreted
EightFetal development continues and hCG continues to be secreted
NineLevels of hCG are now high enough to detect a pregnancy

We're wrapping up day one past transfer, and I've become obsessed with the above chart that I procured from the NYU Fertility Center website. Today I tried to lay around as much as possible while our Wisembies are hopefully hatching.

With a lot of time on my hands to lay around staring at their picture, I decided to name the Wisembies Ace and Base. Ace is the AA embryo and Base just seemed like the right partner to Ace. Hopefully they see the welcome sign down in my uterus and stick around.

Today my mom, dad, sister, niece, and nephew came over at lunch time, so I turned off the TV and spent all afternoon talking with my favorite people. My niece took my husband to play at the playground, and I got to cuddle my infant nephew, who was able to be there because my sister is still on maternity leave.

It felt right having the family together with Ace and Base trying their hardest to join our family. Only time will tell though.

Monday, November 5, 2012

After the transfer

Here's a picture of my Wisembies taken in the embrology lab and then given to me to take home. It's backwards because of PhotoBooth, but you get the gist. The blastocyst you see at the bottom is a perfect AA and the one at the top is solid AB. Last time, we didn't have such good ratings going into our transfer, so that is very hopeful.

I'm back at home with my feet up feeling like maybe I'm pregnant already. :-) I'll know for sure in a week and two days.